The research focus of our department is on regulatory networks of cells and organisms. By applying a range of bioinformatics methods, we hope to contribute to unravel the underlying principles and, at the same time, to develop a couple of tools which may prove useful to the systems biology community. Like our research, our teaching in bioinformatics is very much biology-driven. In this sense, we try to convey the importance and the principles of bioinformatics to students in medicine, biology and computer sciences.